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A patient with HIV presents with dysphagia due to candidiasis. What CD4 count is generally considered a threshold for increased risk of opportunistic infections?

  1. 180 cells/μL

  2. 250 cells/μL

  3. 300 cells/μL

  4. 400 cells/μL

The correct answer is: 180 cells/μL

The appropriate threshold for increased risk of opportunistic infections in patients with HIV is often considered to be a CD4 count of 200 cells/μL. When the CD4 count falls below this level, the immune system becomes significantly compromised, leading to a higher susceptibility to opportunistic infections, including candidiasis, which can cause dysphagia as seen in this patient. A CD4 count of 180 cells/μL indicates a level that is below this critical threshold, marking the patient as being at an increased risk for developing such infections. Therefore, the answer reflects that at this count, clinical vigilance for opportunistic infections is essential. Higher CD4 counts, such as 250, 300, or 400 cells/μL are generally associated with a lower risk of opportunistic infections, thus reinforcing the importance of maintaining a CD4 count above 200 cells/μL for better immune function and reduced risk of such infections in HIV patients.